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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TTC3 All Species: 4.55
Human Site: S1609 Identified Species: 20
UniProt: P53804 Number Species: 5
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P53804 NP_001001894.1 2025 229891 S1609 L D Q S L E I S N T L T N E K
Chimpanzee Pan troglodytes XP_001169868 2025 229900 S1609 L D Q S L E I S N T L T N E K
Rhesus Macaque Macaca mulatta XP_001083947 2010 228378 E1603 T Q K N D G K E K E H E L H L
Dog Lupus familis XP_849567 2000 227315 E1594 A Q K N D G K E K E H E L L L
Cat Felis silvestris
Mouse Mus musculus O88196 1979 223913 Q1573 N T S E M S A Q K N D G F D K
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416727 1934 221483 K1502 V K L E E L I K K S Q D D L K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 93.8 82.7 N.A. 75.3 N.A. N.A. N.A. 36.9 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.5 95.8 88.4 N.A. 84.5 N.A. N.A. N.A. 56.4 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 0 0 N.A. 6.6 N.A. N.A. N.A. 13.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 13.3 13.3 N.A. 20 N.A. N.A. N.A. 33.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 0 0 0 0 0 17 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 34 0 0 34 0 0 0 0 0 17 17 17 17 0 % D
% Glu: 0 0 0 34 17 34 0 34 0 34 0 34 0 34 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 17 0 0 % F
% Gly: 0 0 0 0 0 34 0 0 0 0 0 17 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 34 0 0 17 0 % H
% Ile: 0 0 0 0 0 0 50 0 0 0 0 0 0 0 0 % I
% Lys: 0 17 34 0 0 0 34 17 67 0 0 0 0 0 67 % K
% Leu: 34 0 17 0 34 17 0 0 0 0 34 0 34 34 34 % L
% Met: 0 0 0 0 17 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 17 0 0 34 0 0 0 0 34 17 0 0 34 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 34 34 0 0 0 0 17 0 0 17 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 17 34 0 17 0 34 0 17 0 0 0 0 0 % S
% Thr: 17 17 0 0 0 0 0 0 0 34 0 34 0 0 0 % T
% Val: 17 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _